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March 1991

Cortical Resection for Children With Epilepsy: Perspectives in Pediatrics

Author Affiliations

From the Pediatric Epilepsy Program, The Cleveland (Ohio) Clinic Foundation.

Am J Dis Child. 1991;145(3):314-320. doi:10.1001/archpedi.1991.02160030082027

The potential of cortical resection for epilepsy was first demonstrated by Penfield and Jasper1 at the Montreal Neurologic Institute (Montreal, Quebec) in the 1940s and 1950s. The application of this technique in children was emphasized in the 1960s and 1970s2-8; since then, it has become apparent that early surgery in selected cases may enable children to become seizure free for a normal transition into adulthood. This may prevent some of the difficult psychosocial problems that occur in adults with longstanding epilepsy, including dependency, poor selfesteem, and long-term vocational disability.9 In addition, if epilepsy surgery enables a child to discontinue antiepileptic medication, years of exposure to these drugs can be avoided. As pediatricians become better acquainted with surgical options, patients are benefiting from earlier referral for surgery. The purpose of this review is to inform children's physicians about the indications for referral

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