Denouement and Discussion
Laron-type dwarfism is characterized by marked growth retardation, acromicria (small hands, feet, and chin), obesity, and micropenis. Craniofacial abnormalities include a protruding forehead, saddle nose, and an increased biparietal-bicondylar ratio, all caused by marked underdevelopment of the facial bones. Head circumference is decreased, skeletal maturation is markedly retarded, the bones are very thin, and there is an increased incidence of minor skeletal abnormalities such as slipped femoral epiphyses and Legg-Calve-Perthes disease. The obesity is generalized and there is underdevelopment of muscle mass. Genitalia and gonads are small, and
Laron Z, Klinger B, Grunebaum M, Feingold M, Tunnessen WW. Picture of the Month. Am J Dis Child. 1991;145(4):473–474. doi:10.1001/archpedi.1991.02160040135023
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