By Catherine DeAngelis, 183 pp, with illus, $24.95, Stoneham, Mass, Butterworth Publishers Inc, 1991.
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This is a clear, well-written book that walks the reader through a clinical research project. It begins with defining the research question and ends with critiquing the published project description. The author has consulted respected clinical researchers in writing this text, and her introduction is an excellent précis of the journey from the beginning to the end of a research project. Chapter 1, which discusses the scientific method, is the most difficult chapter to understand and could be simplified in the next edition. Chapters 2 and 3 review the definition of the research question and selection of subjects. Chapter 4 ("Types of Research Models and Methods") is particularly good. It clarifies such difficult concepts as varied study designs by using excellent tables and figures. Chapter 5 discusses data collection, management, and analysis; like chapter 4, its clarification of topics such as statistical tests of significance and data collection methods is
GROOTHUIS JR. An Introduction to Clinical Research. Am J Dis Child. 1991;145(8):945. doi:10.1001/archpedi.1991.02160080123034
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