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July 1993

Hemiplegic Migraine and Moyamoya Disease

Author Affiliations

Department of Neurology Kaiser Permanente Medical Center 27400 Hesperian Blvd Hayward, CA 94545-4297

Am J Dis Child. 1993;147(7):718-719. doi:10.1001/archpedi.1993.02160310020008

Sir.—Hemiplegic migraine is a form of complicated migraine.1 In children, such migraine without headache often manifests initially as transient hemiplegia,2,3 and the symptoms may be indistinguishable from those of transient ischemic attacks (TIAs).

Moyamoya disease is a rare vasculopathy of the intracranial portion of the carotid and vertebral arteries4 and is of unknown origin. Moyamoya disease occurs in children and young adults and causes occlusion of the major cerebral vessels.5-8 Initial signs are usually strokes, seizures, or TIAs.9 After a major neurologic event, cerebral angiography is often used to diagnose moyamoya disease. Moyamoya ("puff of smoke" in Japanese) disease was previously identified from angiograms showing telangiectatic vessels acting as collateral channels to the occluded distal carotid arteries.10 More recently, magnetic resonance imaging (MRI) has been used to identify the abnormal occluded vessels as well as the dilated collateral vessels in the basal ganglia

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