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September 1997

Nutrient Intakes by Young Children in a Prospective Randomized Trial of a Low-Saturated Fat, Low-Cholesterol Diet

Author Affiliations

Department of Pediatrics College of Medicine University of South Florida 1 Davis Blvd, Suite 307, MDC 15 Tampa, FL 33606-3475

Arch Pediatr Adolesc Med. 1997;151(9):960-961. doi:10.1001/archpedi.1997.02170460098024

A recent article in the Archives by investigators in the Department of Pediatrics at the University of Turku, Turku, Finland,1 is the third in a series describing the results of the Special Turku Coronary Risk Factor Intervention Baby Project (STRIP) which investigated the results of feeding infants and children low-fat diets.1-3 The rationale for this study seems to be the unproved assumption that significant atherosclerosis begins at birth and that dietary intervention in infancy will have a major effect on the risk of coronary heart disease in later life. Because the crucial event in clinically marked atherogenesis is the formation of the raised plaque, which does not begin until puberty in boys and much later in girls, the assumption underlying STRIP seems groundless. In fact the Pathobiological Determinants of Atherosclerosis in Youth Research Group4 study, which documented arterial plaque development in male subjects 15 to 34 years