Pathological Case of the Month | Infectious Diseases | JAMA Pediatrics | JAMA Network
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Special Feature
February 1998

Pathological Case of the Month

Author Affiliations


Arch Pediatr Adolesc Med. 1998;152(2):199-200. doi:10.1001/archpedi.152.2.199

THE INFANT pictured in Figure 1 was a 415-g female born at 22 weeks' gestational age to a 17-year-old gravida 2, para 1 mother. The mother's previous pregnancy produced a healthy child. This pregnancy was complicated by a foul-smelling vaginal discharge and abdominal cramps 2 days prior to admission to the hospital. At admission she had a high leukocyte count and fever. After amniocentesis, she was delivered of this female infant, who lived for 8 hours. The placenta weighed 193 g and had necrotizing acute chorioamnionitis (Figure 2 and Figure 3). All 3 umbilical vessels had vasculitis and funisitis. Airspaces were filled with polymorphonuclear leukocytes (Figure 4). Amniotic fluid and postmortem cultures grew Haemophilus influenzae biotype 1.