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Special Feature
March 1998

Pathological Case of the Month

Arch Pediatr Adolesc Med. 1998;152(3):302. doi:

Figure 1. A large, partially calcified intraperitoneal mass.

Figure 2. Grade 1 immature ovarian teratoma with neuroepithelial rosette formation (hematoxylin-eosin, original magnification ×132).

Figure 3. Grade 0 glial implants in omentum (hematoxylin-eosin, original magnification ×66).

Ovarian teratomas are graded by criteria of Robboy and Scully,1 which have been modified by Thurlbeck and Scully2 and Dehner.3 A teratoma with no immature tissue is grade 0; with fewer than 1 low-power field of immature tissue per slide is grade 1; with more than 1 but fewer than 4 low-power fields per slide of immature neuroepithelial foci is grade 2; and a teratoma with consecutive microscopic fields of immature tissue, either immature neuroepithelial or somatic, is grade 3. All grades 1 and 2 ovarian teratomas in children act in a benign fashion. All grade 3 teratomas that exhibit malignant behavior tend to have foci of yolk sac tumor.

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