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Special Feature
May 1998

Pathological Case of the Month

Arch Pediatr Adolesc Med. 1998;152(5):510. doi:

Figure 1. Abdominal computed tomographic scan showing a large hypodense liver mass with irregular calcifications.

Figure 2. A solid sheet of round to polygonal cells with vesicular nuclei, prominent nucleoli, and abundant eosinophilic cytoplasm (hematoxylin-eosin, original magnification ×100).

Figure 3. Neoplastic cells demonstrate an intense intracytoplasmic immunoexpression for vimentin (peroxidase, original magnification ×100). Epithelial membrane antigen was expressed and no reaction to muscle specific actin cytokeratins, and S100 proteins were noted.

Figure 4. Electron microscopy showing a rhabdoid cell with large nucleoli and paranuclear aggregates of intermediate filaments (original magnification ×3900).

Exploratory laparotomy with tumor biopsy was performed (Figure 2 and Figure 3). Neoplastic cells also expressed epithelial membrane antigen. An ultrastructural study was also performed (Figure 4).