Radiological Case of the Month | Critical Care Medicine | JAMA Pediatrics | JAMA Network
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Special Feature
June 2001

Radiological Case of the Month

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Arch Pediatr Adolesc Med. 2001;155(6):733-734. doi:10.1001/archpedi.155.6.733

A FEMALE INFANT weighed 870 g at birth and had Apgar scores of 7 and 8 at 1 and 5 minutes, respectively. She was born at 262/7 weeks' gestation to a mother with advanced malignant pleural mesothelioma.1 A histologic evaluation of the products of conception revealed no evidence of malignancy. Immediately following delivery, the infant developed moderate stridor, grunting, and nasal flaring. She was intubated, received exogenous pulmonary surfactant, and was transferred to the neonatal intensive care unit.

Ventilator assistance was discontinued on day 7 and she was subsequently weaned from continuous positive airway pressure by day 23. Her hospital course remained uneventful until day 54 when edema, discoloration, and proptosis of the right eye were noted. Funduscopy demonstrated immature retinal vasculature and no papilledema or proliferative retinopathy. Computed tomography of the head revealed a soft tissue mass in the intracoronal aspect of the right orbit with ascension of the mass posteriorly into the right cavernous sinus (Figure 1). Ultrasonography confirmed a homogeneous 2.1-cm solid mass in the right retro-orbital region. Doppler interrogation demonstrated prominent flow within the mass (Figure 2).

Ramsey  PSDanilenko-Dixon  DRRamin  KDOgburn  PL  Jr Malignant pleural mesothelioma in pregnancy.  J Matern Fetal Med. 2000;9373- 375Google ScholarCrossref