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    Research Letter
    December 2, 2019

    Placental Weight and Risk of Neonatal Death

    Author Affiliations
    • 1Department of Obstetrics and Gynecology, Akershus University Hospital, Lørenskog, Norway
    • 2Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    • 3Department of Pediatric Research, Oslo University Hospital, University of Oslo, Oslo, Norway
    JAMA Pediatr. 2020;174(2):197-199. doi:10.1001/jamapediatrics.2019.4556

    The placenta is a determinant of fetal growth, and infants who are born small for gestational age have an increased risk of infant death.1,2 Such knowledge suggests that placental factors may be associated with infant death, particularly in deaths shortly after birth.

    Previously, low placental weight has been associated with increased risk of fetal death3 and with cerebral palsy in infants.4 By contrast, in preterm-born children, high placental weight and high placental weight relative to birth weight increased the risks.3,4 These previous findings suggest that placental weight may be associated with neonatal death and that associations may differ by gestational age at birth.