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In This Issue of JAMA Pediatrics
December 2019


JAMA Pediatr. 2019;173(12):1119. doi:10.1001/jamapediatrics.2018.3537

Urashima and colleagues conducted a randomized clinical trial involving 312 newborns to test whether the risks of sensitization to cow’s milk and immediate-type food allergy, including cow’s milk allergy and anaphylaxis, were decreased by avoiding supplementation with cow’s milk formula for at least the first 3 days of life. They found that sensitization to cow’s milk and clinical food allergies may be preventable by avoiding cow’s milk formula supplementation at birth, which is easily and immediately applicable to clinical practice worldwide without the cost and time of therapy.



Continuing Medical Education

Gray and colleagues conducted a 12-week randomized clinical trial with 157 treatment-seeking adolescent cigarette smokers. They found that abstinence rates at the end of treatment (primary outcome) did not differ between groups, but examination of secondary findings revealed that participants given varenicline achieved abstinence earlier and had higher rates of overall abstinence during treatment and at posttreatment follow-up compared with participants given placebo. Treatment-emergent adverse events did not differ between groups.