COVID-19 in Pregnant Women and Their Newborn Infants | Neonatology | JAMA Pediatrics | JAMA Network
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April 22, 2021

COVID-19 in Pregnant Women and Their Newborn Infants

Author Affiliations
  • 1Infectious Disease Section, Department of Pediatrics, Baylor College of Medicine, Houston, Texas
JAMA Pediatr. Published online April 22, 2021. doi:10.1001/jamapediatrics.2021.1046

Pregnant women have long been recognized as a vulnerable population during infectious disease pandemics.1 This was recognized in 1918, during the Spanish influenza pandemic, in which 50% of pregnant women who were infected died. Despite the many advances in critical care since then, similar findings were noted during the 2009 H1N1 pandemic, in which pregnant women were disproportionately more likely to have severe illness, require hospitalization and intensive care, and die than their nonpregnant counterparts.2,3 Similar findings were noted during the more geographically contained novel coronavirus experiences during the past decades, severe acute respiratory syndrome and Middle East respiratory syndrome coronavirus.4 It is therefore predictable that enhanced risks are associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

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