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Special Feature
April 1999

Pathological Case of the Month

Author Affiliations

Copyright 1999 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1999

Arch Pediatr Adolesc Med. 1999;153(4):427-428. doi:

THE PATIENT was a 9-month-old boy who had abnormal findings on an initial newborn screen for hypothyroidism, but a second test showed a normal circulating free thyroxine concentration, with serum thyroid-stimulating hormone concentrations that fluctuated between normal and slightly elevated. He was given replacement thyroid hormone to treat his compensated primary hypothyroidism. During the first few months of life, purplish, firm, nodular lesions were noticed on his abdomen and extremities (Figure 1), with the largest on the wrist and the knee (Figure 2). A biopsy specimen of one of the lesions on his abdomen had the microscopic appearance shown in Figure 3.