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Special Feature
April 6, 2009

Picture of the Month—Diagnosis

Arch Pediatr Adolesc Med. 2009;163(4):384. doi:10.1001/archpediatrics.2009.15-b

The findings of smooth, waxy umbilicated papules as seen in our case are characteristic of molluscum contagiosum. The patient was also diagnosed with human immunodeficiency virus infection with low CD4+T-cell counts. A regression of the skin lesions was seen after commencement of highly active antiretroviral therapy.

Molluscum contagiosum is a viral disorder of the skin characterized by discrete, single or multiple, flesh-colored papules. It is caused by Molluscipoxvirus, a large, double-stranded-DNA virus belonging to the same family as cowpox and smallpox.1There are 4 subtypes, all of which behave clinically identically. Subtype I (75%-90% of cases) is the most common, followed by subtype II.2