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One concern of female childhood and adolescent cancer survivors is the possibility of adverse outcomes among their offspring. Using data from 4 US regions, Mueller and colleagues conducted a population-based study to compare the occurrence of infancy outcomes among offspring of female cancer survivors with a comparison group identified from birth records. The proportion of childhood cancer patients identified with live births ranged from 13% to 17% across the 4 regions, with an overall mean time from diagnosis to delivery of 8.5 years. Infants of childhood cancer survivors were more likely to be born preterm and to weigh less than 2500 g. There was no increased risk of birth malformations or infant death.
This Month in Archives of Pediatrics & Adolescent Medicine. Arch Pediatr Adolesc Med. 2009;163(10):878. doi:10.1001/archpediatrics.2009.189
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