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Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) is hypothesized to describe a group of children with a sudden onset of obsessive-compulsive and tic disorders in the weeks following streptococcal pharyngitis. However, PANDAS as a distinct entity remains controversial. In this comparison of children with streptococcal pharyngitis or viral pharyngitis and well children, the risk of developing PANDAS symptoms in the subsequent 3 months was examined. Perrin and colleagues found that the risk of developing new PANDAS symptoms was not increased in children with streptococcal infection, all of whom were treated, compared with children in the other groups.
This Month in Archives of Pediatrics & Adolescent Medicine. Arch Pediatr Adolesc Med. 2004;158(9):847. doi:https://doi.org/10.1001/archpedi.158.9.847
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