The Current Revolution in Newborn Screening: New Technology, Old Controversies | Neonatology | JAMA Pediatrics | JAMA Network
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Review
August 2007

The Current Revolution in Newborn Screening: New Technology, Old Controversies

Author Affiliations

Author Affiliations: Division of General Pediatrics, and Child Health Evaluation and Research Unit, University of Michigan, Ann Arbor.

Arch Pediatr Adolesc Med. 2007;161(8):767-772. doi:10.1001/archpedi.161.8.767
Abstract

Newborn screening has provided a model of a successful public health screening program for the past 40 years. However, the history of newborn screening is not without controversy. Many of these controversies have been rekindled with the introduction of tandem mass spectrometry, a technology that has greatly increased our ability to detect potential disease in asymptomatic newborns. This review highlights the challenges raised by this and future technological advances as we strive to maintain the success of newborn screening in the 21st century.

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