Amy Sarah Ginsburg, MD, MPH; Tisungane Mvalo, MBBS; Evangelyn Nkwopara, MS; et al.
open access
JAMA Pediatr. 2019;173(1):21-28. doi:10.1001/jamapediatrics.2018.3407
This double-blind, randomized clinical noninferiority trial evaluates whether placebo treatment is significantly inferior to 3 days of oral amoxicillin treatment in HIV-uninfected children aged 2 to 59 months with nonsevere fast-breathing pneumonia in a malaria-endemic region of Malawi, Africa.
James D. O’Leary, MD; Magdalena Janus, PhD; Eric Duku, PhD; et al.
free access
JAMA Pediatr. 2019;173(1):29-36. doi:10.1001/jamapediatrics.2018.3662
This population-based sibling-matched study assesses the association between surgical procedures that require anesthesia in children aged 5 to 6 years and child development in Ontario, Canada.
Erin R. Morgan, MS; Anthony Gomez, BS; Frederick P. Rivara, MD, MPH; et al.
free access
JAMA Pediatr. 2019;173(1):37-43. doi:10.1001/jamapediatrics.2018.3624
This study examines self-reported data from the 2013 and 2016 Behavioral Risk Factor Surveillance System in Washington State to quantify the association between presence of an adult reporting alcohol misuse and children’s living in a home with an unsafely stored firearm.
Caring for the Critically Ill Patient
Heather L. Tubbs-Cooley, PhD, RN; Constance A. Mara, PhD; Adam C. Carle, MA, PhD; et al.
free access
has audio
JAMA Pediatr. 2019;173(1):44-51. doi:10.1001/jamapediatrics.2018.3619
This study evaluates the association of nurse shift-level workloads in the neonatal intensive care unit with missed nursing care using nurse-reported data.
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Audio Author Interview:
Association of Nurse Workload With Missed Nursing Care in the NICU
Sarah B. Mulkey, MD, PhD; Dorothy I. Bulas, MD; Gilbert Vezina, MD; et al.
free access
JAMA Pediatr. 2019;173(1):52-59. doi:10.1001/jamapediatrics.2018.4138
This cohort study compares the use of fetal magnetic resonance imaging and ultrasonography in the identification of brain abnormalities associated with Zika virus.
Kanecia O. Zimmerman, MD, MPH; P. Brian Smith, MD, MPH, MHS; Ann W. McMahon, MD, MS; et al.
free access
JAMA Pediatr. 2019;173(1):60-67. doi:10.1001/jamapediatrics.2018.3227
This study characterizes the duration of clinical trials submitted to the US Food and Drug Administration for pediatric drug approvals, with a focus on drugs used for long-term therapy.
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Editorial
Development of Therapeutics for Children—A Tricky Balancing Act
Michael Cohen-Wolkowiez, MD, PhD; Daniel K. Benjamin Jr, MD, PhD
Thomas J. Hwang, AB; Liat Orenstein, MSc; Aaron S. Kesselheim, MD, JD, MPH; et al.
free access
JAMA Pediatr. 2019;173(1):68-74. doi:10.1001/jamapediatrics.2018.3416
This cohort study evaluates the characteristics, completion rate, and transparency of study design and results for mandatory pediatric postmarketing studies required under the Pediatric Research Equity Act.
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Editorial
Development of Therapeutics for Children—A Tricky Balancing Act
Michael Cohen-Wolkowiez, MD, PhD; Daniel K. Benjamin Jr, MD, PhD
Shiraz Badurdeen, MRCPCH; Andrew Marshall, DPhil; Hazel Daish, MRCPCH; et al.
open access
JAMA Pediatr. 2019;173(1):75-85. doi:10.1001/jamapediatrics.2018.4038
This systematic review and meta-analysis examines the safety and efficacy of bacillus Calmette-Guérin vaccination at birth or later points in infants who are preterm and/or had low birth weights compared with ones who are full term and/or had normal birth weights.
Lief Pagalan, MSc; Celeste Bickford, BSc; Whitney Weikum, PhD; et al.
free access
JAMA Pediatr. 2019;173(1):86-92. doi:10.1001/jamapediatrics.2018.3101
This large population-based Canadian cohort study evaluates the association between prenatal exposures to airborne pollutants and autism spectrum disorder.
Jeffrey A. SoRelle, MD; Drew M. Thodeson, MD; Susan Arnold, MD; et al.
free access
online only
JAMA Pediatr. 2019;173(1):e182302. doi:10.1001/jamapediatrics.2018.2302
This study investigates the utility of reinterpreting the genomic test results of pediatric patients who previously underwent genomic epilepsy testing.
Andrée-Anne Ledoux, PhD; Ken Tang, PhD; Keith O. Yeates, PhD; et al.
free access
online only
JAMA Pediatr. 2019;173(1):e183820. doi:10.1001/jamapediatrics.2018.3820
This multicenter cohort study describes the natural progression of symptom change by age group (5-7, 8-12, and 13-18 years) and sex and develops centile curves to inform families about children after concussion recovery.