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This Viewpoint describes how recommendations for optimizing the treatment of pediatric sepsis may have resulted in overdiagnosis and overuse of antibiotics.

This study of all pediatric patient deaths in a US national multicenter database seeks to determine the epidemiology and clinical characteristics of patients declared brain dead in pediatric intensive care units.

This cohort study analyzes infants who received allogeneic hematopoietic cell transplants at age 12 months or younger to determine changes over time in complications and outcomes.

This Clinical Guideline Synopsis discusses the 2018 Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN).

This randomized clinical trial examines the effect of folic acid supplementation in pregnant women who smoke tobacco on infant birth weight, infant status as small for gestational age, and fetal growth restriction.

Notice of Retraction and Replacement. Hawkins et al. Trends in weight loss efforts among US adolescents with overweight and obesity. JAMA Pediatr. 2018;172(8):782-784

This Viewpoint reviews the debate about germline gene editing in the context of previous debates about in vitro fertilization and other notable technologies.

This cohort study evaluates the association of infant temperament with overweight and obesity status at ages 2 to 5 years in children born to mothers who experienced gestational diabetes mellitus.

This secondary analysis of the Antenatal Late Preterm Steroids trial compares the cost-effectiveness of treatment with antenatal corticosteroids with no treatment for women at risk for late preterm delivery.

This study examines the use of intravenous acetaminophen in children and its rising costs.

This Viewpoint suggests alternative frameworks through which to evaulate scholarly quality improvement.

This cohort study examines the prevalence and severity of atopic dermatitis as well as sleep duration and quality at multiple periods among young children enrolled in the Avon Longitudinal Study of Parents and Children in the United Kingdom.

This article calls for the establishment of an essential medicine list focused on chemotherapy and supportive care agents for pediatric cancer.

This study examined the self-reported quality of life in an international cohort of 11-year-old children with birth weights of 500 to 1250 g.