Author Affiliations: Department of Psychology, Metropolitan State University, St Paul, Minnesota (Dr Spielmans); Discipline of Psychiatry, Adelaide University, Adelaide, South Australia (Dr Jureidini), and Discipline of Psychiatry, University of Queensland, St Lucia, Queensland (Dr Purssey), Australia; and Department of Psychological Medicine, Cardiff University, Hergest Unit, Bangor, Wales (Dr Healy).
In recent articles, Gibbons and colleagues1,2 concluded that antidepressants lowered suicidality relative to placebo among adult patients while demonstrating no difference in suicidality among youths; they further concluded that antidepressants possessed robust efficacy vs placebo. However, there are several problems with the underlying data and their choice of suicidality measures.
Spielmans GI, Jureidini J, Healy D, Purssey R. Inappropriate Data and Measures Lead to Questionable Conclusions. JAMA Psychiatry. 2013;70(1):121–123. doi:10.1001/jamapsychiatry.2013.747