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March 2014

Mortality in Patients With Traumatic Brain Injury

Author Affiliations
  • 1Department of Psychiatry Administration, University of Iowa, Iowa City
JAMA Psychiatry. 2014;71(3):234-235. doi:10.1001/jamapsychiatry.2013.4241

The current issue of JAMA Psychiatry includes an important article on premature mortality among patients with traumatic brain injury (TBI) in Sweden between 1969 and 2009.1 According to the study by Fazel et al,1 among 218 300 patients with a TBI compared with age- and sex-matched controls without brain injury (10 to 1 match, n = 2 163 190) and unaffected siblings of TBI patients (n = 150 513), there was a 3-fold increased odds of all-cause mortality, adjusted for sociodemographic confounders (adjusted odds ratio [aOR], 3.2; 95% CI, 3.0-3.4), among patients who survived at least 6 months after TBI compared with general population controls or unaffected siblings (aOR, 2.6; 95% CI, 2.3-2.8). The increased rates of mortality were related to injury (aOR, 4.3; 95% CI, 3.8-4.8), assault (aOR, 3.9; 95% CI, 2.7-5.7), or suicide (aOR, 3.3; 95% CI, 2.9-3.7).

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