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Comment & Response
February 2014

Early Medication Discontinuation on Long-term Recovery Outcome in First-Episode Psychosis

Author Affiliations
  • 1Department of Psychiatry, University of Hong Kong, Hong Kong SAR, China
  • 2State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, Hong Kong, China
JAMA Psychiatry. 2014;71(2):207-208. doi:10.1001/jamapsychiatry.2013.3697

To the Editor Wunderink et al1 studied the long-term effects of early dosage reduction or discontinuation (DR) of antipsychotic medication vs maintenance treatment (MT) on recovery in patients with remitted first-episode psychosis. It makes an important contribution to the literature and has intriguing clinical implications. However, we would like to clarify some issues before concluding the longitudinal benefits of DR over MT in the study.

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