Modeled after the Framingham Heart Study, the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) is designed to identify salient risk and protective factors regarding suicide, adverse mental health outcomes, and functional impairment. This groundbreaking initiative is investigating a wide range of domains, from large administrative data sets to behavioral, neurobiological, and genetic markers. It will certainly have a great impact on the field of psychiatry.