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Letters to the Editor
March 1998

Repetitive Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder

Arch Gen Psychiatry. 1998;55(3):276-279. doi:

Several laboratories using functional neuroimaging techniques have recently reported that patients with posttraumatic stress disorder (PTSD) have increased blood flow or metabolism in right limbic, paralimbic, and frontal cortical structures when recalling the traumatic event associated with their symptoms.1-4 This observation is consistent with several studies implicating preferential right hemispheric involvement in the experience of unpleasant emotion.5-10 Taken together, these findings suggest that right limbic and paralimbic structures are intimately involved with the emotional symptoms associated with traumatic memories,11 and could potentially be the target of neurobiological treatment strategies.