Kendler et al1 have used latent class analysis to reclassify the psychoses into new categories that differ from those originally provided by Emil Kraepelin and those presently designated in DSM-IV. Since psychosis is heterogeneous in symptom expression, course, and outcome, and since there are no specific biologic markers, we are continually on a quest to subdivide them into more homogeneous, presumably etiologic, subgroups. However, it is unclear whether Kendler's system provides the definitive answers.