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October 1999

Toward the Identification of Core Psychopathological Processes?

Arch Gen Psychiatry. 1999;56(10):929-931. doi:10.1001/archpsyc.56.10.929

RECENT ADVANCES in the development of the classification of mental disorders through the adoption of a basically "atheoretical," empirically based, descriptive approach have enhanced the reliability, coverage across diverse settings, and clinical and research utility of explicit diagnostic criteria and specified diagnostic algorithms.1,2 However, the diagnosis of specific disorders is still heavily dependent on diagnostic interviews rather than pathognomonic markers, and convincing clinical and nosological validation is lacking in terms of prognostic value and stability, family and genetic findings, and laboratory findings.3

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