[Skip to Navigation]
Sign In
Citations 0
Letters to the Editor
March 2002

D-Lactate and the False Suffocation Alarm

Arch Gen Psychiatry. 2002;59(3):287-288. doi:

In reply

Dr Davies states that Klein1 incorrectly assumes that D-lactate is not metabolized by humans; thus, that our demonstration of panic generation in panic patients by D-lactate infusion2 does not rule out lactate metabolism as a possible panicogenic process. He cites articles anteceding ours to indicate our ignorance. However, the literature of that time was still controversial since humans lack D-lactate dehydrogenase. It was not until 1993 that Yasuda et al3 attributed D-lactate metabolism in humans to a specific enzyme.

Add or change institution