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Comment & Response
September 2015

Mortality Risk With Mirtazapine and Estimating Suicide Risk

Author Affiliations
  • 1Northwest Clinical Research Center, Bellevue, Washington
  • 2Department of Psychiatry, Duke University School of Medicine, Durham, North Carolina
  • 3Department of Psychiatry and Human Behavior, Brown University, Providence, Rhode Island
JAMA Psychiatry. 2015;72(9):949. doi:10.1001/jamapsychiatry.2015.1049

To the Editor We appreciate the opportunity to respond to Dr Howland’s letter1 regarding our article.2 First and foremost, Dr Howland assumed that we reported that deaths among patients with depression assigned to mirtazapine were due to toxicity associated with an overdose of mirtazapine in these cases. However, we did not suggest such a possibility.

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