In Reply We agree that our results are based on a small number of respondents who met criteria for major depressive disorder and mood disorders. We were transparent about this and noted sample size as the study’s primary limitation. As stated in our article,1 the National Survey of American Life (NSAL) remains one of the best data sets for this study. We considered using National Comorbidity Survey Replication data; however, it contained a limited number of rural cases. Given the sample size limitation, our article1 emphasized the importance of future research examining major depressive disorder and mood disorders among rural African American individuals with other samples.