Associations Between Cannabis Use and Physical Health Problems in Early Midlife: A Longitudinal Comparison of Persistent Cannabis vs Tobacco Users | Adolescent Medicine | JAMA Psychiatry | JAMA Network
[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.234.207.100. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    1 Comment for this article
    EXPAND ALL
    On the decline in periodontal health for heavy cannabis users
    Dr. Leonardo Della Pietra | Uni Heidelberg, Physikalisches Institut, Alumni
    Do you have an explanation for the observed influence of cannabis use on periodontal health which can differentiate between the following:


    -Negative effect of the cannabis use due to act of smoking itself.

    -Negative effect of cannabis-specific chemicals at the "medical" level (like influence to the immune system).

    -Negative effect due to a change in "mechanical" mouth parameters (like mastication rate).  I would like to point the attention to a phenomenon well know to cannabis users: cottonmouth.  Many users experience a pronounced reduction in the saliva flow.  This coupled with food craving and increased laziness (decreased probability of using the toothbrush after food assumption) may well play against gum health.

    Reference:

    http://www.ncbi.nlm.nih.gov/pubmed/18637392




    CONFLICT OF INTEREST: None Reported
    READ MORE
    Original Investigation
    July 2016

    Associations Between Cannabis Use and Physical Health Problems in Early Midlife: A Longitudinal Comparison of Persistent Cannabis vs Tobacco Users

    Author Affiliations
    • 1Department of Psychology, Arizona State University, Tempe
    • 2Department of Psychology and Neuroscience, Duke University, Durham, North Carolina
    • 3Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina
    • 4Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, London, England
    • 5Department of Emergency Medicine, Violence Prevention Research Program, University of California, Davis
    • 6Department of Prevention and Social Medicine, Dunedin School of Medicine, Dunedin, New Zealand
    • 7Dunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand
    • 8Department of Oral Sciences, Sir John Walsh Research Institute, School of Dentistry, University of Otago, Dunedin, New Zealand
    JAMA Psychiatry. 2016;73(7):731-740. doi:10.1001/jamapsychiatry.2016.0637
    Abstract

    Importance  After major policy changes in the United States, policymakers, health care professionals, and the general public seek information about whether recreational cannabis use is associated with physical health problems later in life.

    Objective  To test associations between cannabis use over 20 years and a variety of physical health indexes at early midlife.

    Design, Setting, and Participants  Participants belonged to a representative birth cohort of 1037 individuals born in Dunedin, New Zealand, in 1972 and 1973 and followed to age 38 years, with 95% retention (the Dunedin Multidisciplinary Health and Development Study). We tested whether cannabis use from ages 18 to 38 years was associated with physical health at age 38, even after controlling for tobacco use, childhood health, and childhood socioeconomic status. We also tested whether cannabis use from ages 26 to 38 years was associated with within-individual health decline using the same measures of health at both ages.

    Exposures  We assessed frequency of cannabis use and cannabis dependence at ages 18, 21, 26, 32, and 38 years.

    Main Outcomes and Measures  We obtained laboratory measures of physical health (periodontal health, lung function, systemic inflammation, and metabolic health), as well as self-reported physical health, at ages 26 and 38 years.

    Results  The 1037 study participants were 51.6% male (n = 535). Of these, 484 had ever used tobacco daily and 675 had ever used cannabis. Cannabis use was associated with poorer periodontal health at age 38 years and within-individual decline in periodontal health from ages 26 to 38 years. For example, cannabis joint-years from ages 18 to 38 years was associated with poorer periodontal health at age 38 years, even after controlling for tobacco pack-years (β = 0.12; 95% CI, 0.05-0.18; P <.001). Additionally, cannabis joint-years from ages 26 to 38 years was associated with poorer periodontal health at age 38 years, even after accounting for periodontal health at age 26 years and tobacco pack-years (β = 0.10; 95% CI, 0.05-0.16; P <.001) However, cannabis use was unrelated to other physical health problems. Unlike cannabis use, tobacco use was associated with worse lung function, systemic inflammation, and metabolic health at age 38 years, as well as within-individual decline in health from ages 26 to 38 years.

    Conclusions and Relevance  Cannabis use for up to 20 years is associated with periodontal disease but is not associated with other physical health problems in early midlife.

    ×