Carefully done meta-analyses constitute a major advance compared with expert opinion and nonsystematic attempts at summarizing, synthesizing, and integrating information. Meta-analyses serve many fields in summarizing an increasing stream of data and, for clinical purposes, streamlining information for decision making. However, there are flaws and caveats that threaten the validity and utility of meta-analyses.1
Ioannidis JPA. Meta-analyses Can Be Credible and Useful: A New Standard. JAMA Psychiatry. 2017;74(4):311–312. doi:10.1001/jamapsychiatry.2017.0035
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