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Invited Commentary
July 2017

A Meta View on Meta-analyses

Author Affiliations
  • 1Division of Psychiatry I, Department of Psychiatry, Psychotherapy, and Psychosomatics, Medical University Innsbruck, Innsbruck, Austria
JAMA Psychiatry. 2017;74(7):684-685. doi:10.1001/jamapsychiatry.2017.1167

Meta-analyses are definitely en vogue. A quick PubMed search using the key words “schizophrenia and meta-analysis” shows results that increase from 22 to 149 and 301 from 1996 to 2006 and 2016. Restricting the search to “schizophrenia and treatment and meta-analysis” yielded 13 results that grew to 86 and 140. In this issue of JAMA Psychiatry, Correll et al1 provide a new take on this development by subjecting 29 meta-analyses on cotreatment strategies added to antipsychotic monotherapy in schizophrenia to a “meta-meta-analysis.” Irrespective of the results of their undertaking, in which they refute findings from an earlier report that they authored,2 their novel approach and the value of meta-analyses warrant commentary.