To the Editor In a recent meta-analysis in JAMA Psychiatry, Pillinger et al1 tackled a significant issue, that is, whether schizophrenia indicates an inherent risk for impaired glucose homeostasis. This study analyzed 16 studies, with 731 patients and 614 controls. Results showed that glucose homeostasis becomes impaired at the onset of schizophrenia, indicating that patients with schizophrenia are at increased risk for diabetes. The authors made an important contribution to this complex clinical problem; however, the conclusion might be a little premature.
Cui X, Liu J, Luo X. First-Episode Schizophrenia and Diabetes Risk. JAMA Psychiatry. 2017;74(7):762–763. doi:10.1001/jamapsychiatry.2017.0905
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