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Comment & Response
September 2017

Ketamine for the Treatment of Depression

Author Affiliations
  • 1Research Center for Evidence-Based Medicine, Tabriz University of the Medical Sciences, Tabriz, Iran
  • 2Department of Anesthesiology and Intensive Care Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
JAMA Psychiatry. 2017;74(9):971. doi:10.1001/jamapsychiatry.2017.1779

To the Editor There is now convincing evidence that ketamine has properties to provide prompt antidepressant effects, especially in patients with resistant mood and anxiety disorders.1 Eventually, ketamine will be included in our daily practice. However, in addition to the concerns addressed by Sanacora et al,1 there are a few further complications to be taken into consideration by any practitioner.