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February 2018

A Call to Action for Treatment of Comorbid Tobacco and Alcohol Dependence

Author Affiliations
  • 1Center for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston
JAMA Psychiatry. 2018;75(2):121-122. doi:10.1001/jamapsychiatry.2017.3542

Comorbid addictive disorders are associated with tremendous morbidity and mortality, yet our knowledge base for their treatment remains very limited. No comorbid disorder is more common than the highly harmful combination of nicotine dependence and alcohol addiction; they literally go hand in hand. This issue of JAMA Psychiatry includes a report on the randomized clinical trial on varenicline tartrate used in combination with medical management to treat alcohol addiction and cigarette smoking.1 This placebo-controlled clinical trial seeks to contribute to the needed evidence base by assessing the effect of varenicline treatment on alcohol and tobacco use outcomes in alcohol-dependent adults who engage in tobacco use at least twice weekly.

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