Late adolescence, between the ages of 15 and 19 years, represents a critical stage in life in which young people develop a sense of identity and independence as they transition to adulthood. This stage in life also involves pressures of maturation, academic performance expectations, and changing social roles. Compound these pressures with economic and psychosocial adversity in childhood and early adolescence, including abuse and neglect at home or racial/ethnic, gender, and sexual discrimination, and there emerges an increasing crisis in adolescents’ mental health. Worldwide, the prevalence of mental health disorders (eg, depression, anxiety) increases markedly during late adolescence, reaching a peak during early adulthood (ages 20-24 years).