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Comment & Response
November 2018

Disturbing Lack of Early Intervention Studies in Bipolar Disorder—Reply

Author Affiliations
  • 1Department of Psychiatry, The Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York
  • 2Department of Psychiatry and Molecular Medicine, Hofstra Northwell School of Medicine, Hempstead, New York
  • 3The Feinstein Institute for Medical Research, Manhasset, New York
  • 4Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany
JAMA Psychiatry. 2018;75(11):1202-1203. doi:10.1001/jamapsychiatry.2018.2399

In Reply We thank Post for his letter regarding our article, “Comparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis: A Systematic Review, Meta-analysis, and Meta-regression.1 Post suggests a disparity in the allocation of research resources (especially by the National Institute of Mental Health [NIMH]) for the study of early-phase psychosis (identified by Post as prodromal schizophrenia) vs early prodromal bipolar disorder and points out that bipolar disorder in children is more common than psychosis and that bipolar disorder carries a poor long-term outcome.

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