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Editorial
April 17, 2019

Can Network Meta-analysis Substitute for Direct Comparisons in Psychotherapy Trials?

Author Affiliations
  • 1University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
JAMA Psychiatry. Published online April 17, 2019. doi:10.1001/jamapsychiatry.2019.0243

Affecting more than 10% of the population, depression ranks as the leading cause of disability worldwide and remains a major public health problem.1 First-line treatments for depression include pharmacotherapy and psychotherapy.2 Despite evidence supporting psychotherapy as an effective treatment for depression, relatively little is known about how best to deliver it. In this issue of JAMA Psychiatry, Cuijpers et al3 examine whether an evidence-based psychotherapy for depression, cognitive behavior therapy (CBT), is comparably effective when delivered in a variety of formats.

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