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May 22, 2019

Targeting Cognition and Networks Through Neural Oscillations: Next-Generation Clinical Brain Stimulation

Author Affiliations
  • 1Department of Psychiatry, University of Minnesota, Minneapolis
  • 2The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge
JAMA Psychiatry. Published online May 22, 2019. doi:10.1001/jamapsychiatry.2019.0740

Mental disorders often involve difficulty with complex cognitive functions, such as decision making, emotional self-regulation, or behavioral adaptation to changing circumstances. Those functions arise from the carefully timed and orchestrated synchrony of activity across multiple structures1—in other words, from network activity. It should therefore be possible to treat mental disorders by identifying abnormalities in that network activity and restoring them to healthy patterns.