To the Editor Pettersson et al1 report that reduced fetal growth measured as birth weight was associated with increased risk of mental disorders in offspring. The authors adjusted for gestational age, sex, date of birth, and birth order but not for maternal smoking during the pregnancies. Within-sibling pair comparison allowed to control for time-invariant familial unmeasured confounders.
Aubin H, Berlin I, Ekblad M. Exploring the Association of Sex Differences and Exposure to Maternal Smoking With Low Fetal Growth. JAMA Psychiatry. 2019;76(7):766. doi:10.1001/jamapsychiatry.2019.1130
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