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Comment & Response
July 3, 2019

Pharmacological Management of Delirium

Author Affiliations
  • 1Oslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway
  • 2American Delirium Society, Milwaukee, Wisconsin
  • 3Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 4European Delirium Association
  • 5UMC Utrecht Brain Center, Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands
JAMA Psychiatry. 2019;76(9):983. doi:10.1001/jamapsychiatry.2019.1513

To the EditorJAMA Psychiatry published a network meta-analysis on pharmacological interventions for delirium in which the authors conclude that “…haloperidol plus lorazepam seems to be a superior therapeutic choice in patients with delirium.”1 As delirium is an important health care problem, initiatives for improvement are applauded. However, we would like to point out some concerns arising from the conclusions from this article.