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Comment & Response
July 31, 2019

Factors Associated With Brain Heterogeneity in Schizophrenia—Reply

Author Affiliations
  • 1Norwegian Centre for Mental Disorders Research, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway
  • 2Department of Psychology, University of Oslo, Oslo, Norway
JAMA Psychiatry. Published online July 31, 2019. doi:10.1001/jamapsychiatry.2019.1855

In Reply We thank De Peri and Vita for their thoughtful comments on our recent study of brain structure heterogeneity in patients with schizophrenia.1 They point out some methodological aspects important for interpreting our results and discuss important challenges facing clinical neuroimaging as the field moves toward big data and large-scale integration of cohorts.

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