For more than 20 years, there have been rumbles about banning the P value,1-3 because it is so often misused, miscomputed, and, even when used and computed correctly, misinterpreted. Consequently, findings that affect medical decision-making, policy, and research are often misled by the very research that is supposed to provide their evidence base.4 Recently, such rumbles have increased.5-7 Is now the time to ban the P value in all medical research?