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September 11, 2019

When Improving Symptoms Is Not Enough—Is It Time for Next-Generation Interventions for Obsessive-Compulsive Disorder?

Author Affiliations
  • 1Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
  • 2Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden
JAMA Psychiatry. 2020;77(1):9-10. doi:10.1001/jamapsychiatry.2019.2335

Advances in the last 4 decades have enormously improved the lives of persons with obsessive-compulsive disorder (OCD), a condition once thought to be both rare and untreatable. We now know that OCD is both common and treatable. Most individuals with OCD experience symptom relief after receiving evidence-based psychological and/or pharmacological treatments that were initially developed throughout the 1970s and 1990s (namely, cognitive-behavior therapy [CBT] and serotonin reuptake inhibitors). However, challenges remain.

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    1 Comment for this article
    Apparent Error
    Richard Faulk, MD |
    The article states that "the risks of death by natural or unnatural causes in individuals with OCD were 68% and approximately 160 times higher." However, the source cited does not say that the risk of unnatural death is 160 times higher, but only 2.61 times higher: "The risk of death by natural or unnatural causes was significantly higher among persons with OCD (MRR, 1.68 [95% CI, 1.31-2.12] for natural causes; MRR, 2.61 [95% CI, 1.91-3.47] for unnatural causes) than among the general population."