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Comment & Response
October 2, 2019

Concerns Regarding a Meta-analysis Comparing Psychotherapy With Medications for Posttraumatic Stress Disorder

Author Affiliations
  • 1Guangzhou Huiai Hospital, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China
  • 2The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital & the Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China
  • 3Unit of Psychiatry, Institute of Translational Medicine, Faculty of Health Sciences, & Center for Cognition and Brain Sciences, University of Macau, Macao SAR, China
JAMA Psychiatry. 2020;77(2):215-216. doi:10.1001/jamapsychiatry.2019.2924

To the Editor We read the network meta-analysis on pharmacological, psychotherapeutic, and combination treatments for posttraumatic stress disorder (PTSD) published by Merz et al1 with great interest. In this meta-analysis, the authors found that psychotherapy alone and the combination of pharmacological and psychotherapeutic treatments were significantly associated with better outcomes than pharmacotherapy alone at long-term follow-up assessment, while all approaches demonstrated similar results at the end of short-term treatment. We have some concerns about this network meta-analysis.

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