“Mental disorders are chronic diseases of the young.”Thomas R. Insel, MD, and Wayne S. Fenton, MD1
“Mental disorders are chronic diseases of the young.”
The current paradigm for understanding and treating mental disorders is in crisis. The limited availability of existing treatments is exacerbated by their lack of efficacy for some of the most disabling features of major syndromes, such as impairments in cognitive and functional domains. Despite the promises of genetics and translational neuroscience, causal mechanisms of major syndromes remain to be clearly identified. As a result, development of novel pharmacological therapies has also largely stalled.
Uhlhaas PJ, McGorry PD, Wood SJ. Toward a Paradigm for Youth Mental Health. JAMA Psychiatry. 2021;78(5):473–474. doi:10.1001/jamapsychiatry.2020.3905
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