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Comment & Response
September 29, 2021

Association of Alcohol With Cortical Thickness in Adolescents—Reply

Author Affiliations
  • 1Department of Psychiatry, University of Vermont Larner College of Medicine, Burlington
JAMA Psychiatry. 2021;78(11):1284-1285. doi:10.1001/jamapsychiatry.2021.2790

In Reply We thank Kung et al for their thoughtful comments regarding the association of alcohol use with our findings.1 The potential confounding or interactive associations of alcohol use when investigating cannabis associations is a perennial challenge with human research, but a number of analyses lead us to conclude that the cortical thinning we reported was most strongly associated with cannabis exposure.

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