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Research Letter
December 1, 2021

Deletion of Loss-of-Function–Intolerant Genes and Risk of 5 Psychiatric Disorders

Author Affiliations
  • 1Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
  • 2Deep Genomics Inc, Toronto, Ontario, Canada
  • 3The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada
  • 4Department of Pediatrics, Université de Montréal, Montreal, Quebec, Canada
  • 5UHC Sainte-Justine Research Center, Montreal, Quebec, Canada
  • 6Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada
  • 7McLaughlin Centre, University of Toronto, Toronto, Ontario, Canada
  • 8Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
  • 9Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada
  • 10Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
  • 11Department of Physiology, University of Toronto, Toronto, Ontario, Canada
JAMA Psychiatry. 2022;79(1):78-81. doi:10.1001/jamapsychiatry.2021.3211
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