[Skip to Navigation]
Views 304
Citations 0
Comment & Response
November 24, 2021

Limitations in Research on Maintenance Treatment for Individuals With Schizophrenia

Author Affiliations
  • 1Research and Development, Goodmayes Hospital, North East London National Health Service Foundation Trust, Goodmayes, Ilford, United Kingdom
  • 2Camden and Islington NHS Foundation Trust, London, United Kingdom
  • 3Pharmacy Department, South London and Maudsley National Health Service Foundation Trust, London, United Kingdom
JAMA Psychiatry. Published online November 24, 2021. doi:10.1001/jamapsychiatry.2021.3400

To the Editor We appreciate the clinical value of the dose-response meta-analysis performed by Leucht and colleagues.1 The interpretation provided was that doses above 5 mg/d risperidone equivalent do not provide additional protection against relapse, while the risk of relapse increases rapidly (and apparently hyperbolically) for doses less than 2.5 mg/d risperidone equivalent.

Add or change institution
Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    ×