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Letters to the Editor
June 2000

Hippocampal and Superior Temporal Gyrus Volume in First-Episode Schizophrenia

Arch Gen Psychiatry. 2000;57(6):618-619. doi:

In reply

We thank Hirayasu and colleagues for their letter in response to our article on hippocampal volumes in patients with first-episode psychosis.1 We note that their first-episode study2 also examined patients with first-episode psychosis and included patients with schizophrenia/schizophreniform and affective psychosis. Few studies to date have examined the specificity of brain structural abnormalities to schizophrenia and no previous studies using high-resolution images have examined this issue.